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2. Symptoms: Skin and Nervous System

The toxicity caused by uremia can result in nervous system symptoms such as peripheral neuropathy, cognitive decline, seizures, sensory dysfunction, insomnia, and muscle cramps. Uremia also affects the skin by making it dry and itchy, and causes uremic frost -- urea crystals deposited on the surface of the skin.

Itchy skin symptom HeikeKampe / Getty Images
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