Certain compounds in the body called advanced glycation end products (AGEs) are created when protein or fat combine with sugar in the blood. When in excess, they exacerbate cell aging and deterioration, and people with diabetes have a higher concentration of AGEs. Scientists speculate that higher blood sugar levels may encourage the formation of these proteins, which are implicated in many diabetes-related complications such as nerve, eye, kidney, and heart diseases. Researchers are studying therapies that aim to stop AGEs from collecting in large numbers. Lysine may help reduce the formation of AGEs, thereby reducing the risk of diabetes complications.

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