Some studies suggest that lysine may help treat clinical anxiety and disorders such as schizophrenia. Especially in the latter, lysine may reduce severe anxiety-like symptoms when added as a supplement to conventional therapy. Based on research studies, it appears that lysine works by lowering the stress hormone cortisol and can be used either alone or in combination with the amino acid arginine. Lysine also shows potential to improve digestive problems triggered by stress, such as diarrhea associated with irritable bowel syndrome (IBS).
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