Excessive white adipose tissue (WAT) leads to obesity while brown adipose tissue (BAT) dissipates energy through thermogenesis. Research indicates that activating BAT and inducing WAT browning could help combat the epidemic. Experts think gut bacteria are largely responsible for these processes. Resveratrol, a well-documented polyphenol, acts as a prebiotic, enhancing the composition of the gastrointestinal microbiota. Found in red wine, peanuts, and fruits such as berries and grapes, resveratrol has demonstrated remarkable anti-obesity potential in animal and human studies. In clinical trials, total weight, fat mass, body mass index, and waist circumference all decreased significantly following supplementation with the compound, though more human studies are needed. Scientists are still exploring the mechanisms by which the plant compound works, but research points to metabolic pathways, including adipogenesis, fatty acid oxidation, lipolysis, and lipogenesis.
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