Complexion is affected by various factors including genetics and exposure to sunlight. However, pale skin is also a symptom of vitamin B12 deficiency. Lack of healthy red blood cells carrying adequate oxygen can cause the skin to take on a paler appearance. With a deficiency, the red blood cells can be extremely weak and break easily. This causes the release of a pigment called bilirubin. Excess bilirubin causes the skin to take on a yellow hue, known as jaundice.

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