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3. Morvan’s Syndrome

Some individuals with Isaacs’ syndrome develop a life-threatening complication: Morvan’s syndrome. This autoimmune disease has many of the same symptoms as Isaacs’ syndrome but its primary effect is severe insomnia that causes a complete lack of sleep for weeks or months in a row. A lack of this nature has many physiological effects, as well as hallucinatory behavior, memory loss, and personality changes.

extreme insomnia lack sleep valentinrussanov / Getty Images

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