8. Medications
A few medications are known to cause lupus, primarily procainamide, which treats heart arrhythmias, and hydralazine, used to treat high blood pressure. People taking procainamide have about a 30 percent chance of developing lupus; for hydralazine, it's between five and ten percent.
Drug-induced lupus can take weeks or months to develop, so it can be hard to diagnose. Joint pain is often the first symptom and occurs in 90 percent of cases.
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