Facts About Lupus

3. The Role of Genetics in Lupus Flares

Scientists do not fully understand why immune systems behave differently in some individuals. What is known is that a combination of genetic factors and environmental influences can put certain individuals at higher risk of developing lupus than others. Those with a family history of lupus are more likely to develop similar problems with autoimmunity. Exposure to ultraviolet light, smoking, puberty, pregnancy, induced hormonal changes, and certain infections are linked to the disease. The development of lupus connected to the Epstein-Barr virus is also a primary risk factor. It is most commonly found in women of childbearing age between the ages of 15 and 45, though everyone is at risk of developing the condition.