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8. Complications

While many of CREST syndrome’s effects are visible, the worst complications occur under the skin.

  • CREST syndrome that affects the intestine can cause diarrhea, bloating, weight loss, malnutrition, and constipation.
  • Raynaud’s phenomenon can lead to gangrene and sometimes requires amputation.
  • Excess collagen can collect in the lungs’ air sacs, inhibiting breathing.
  • High blood pressure can result in heart or kidney failure.
  • Dental problems from acid reflux and gum tissue changes can eventually cause teeth to loosen or fall out.

doctor patient complications TommL / Getty Images

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Disclaimer

This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.