NNRTIs bind to the HIV-1 reverse transcriptase enzymes and stop it from turning its own RNA into new DNA, thereby preventing replication of the virus. NNRTIs can reduce the viral load greatly, lessen the likelihood of experiencing resistance to medicines, and diminish the symptoms of the virus. This regimen treats both HIV infection and AIDS. Side effects can include bone-marrow suppression, vomiting, muscle and abdominal pain, and rash.
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