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2. Protease Inhibitors (PIs)

Protease enzymes, which are produced in the stomach, play an important role in our bodies, such as immune support, blood clotting, cell division, and protein recycling. Medications that block viral proteases are useful for treating HIV. Protease inhibitors, or PIs, bind to proteases the HIV virus uses to replicate itself. This reduces the viral load and slows HIV progression. Side effects can include insulin resistance, liver problems, and a notable change in how food tastes.

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