Sometimes, people with esophageal cancer experience pain or discomfort at the center of the chest. Others feel pressure or a burning sensation. These sensations are not necessarily direct symptoms of esophageal cancer; they are usually fringe effects. Acid reflux, heartburn, or gastroesophageal reflux disease can all cause chest pain and are also symptoms of esophageal cancer. In some instances, a person with esophageal cancer has a sensory disorder that causes hypersensitivity of the esophagus. Additionally, some experts suggest chest pain is a physical manifestation of anxiety.

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