The urge to release urine frequently is a symptom of bladder cancer, as well as many other conditions and events including urinary tract infections, diabetes, an enlarged prostate, pregnancy, certain medications, and other health conditions that affect the kidney or bladder. Bladder cancer tumors grow inside the bladder, causing signals that tell the brain the bladder is full to be sent more frequently. Cancer cells can also irritate the bladder walls. Some people with bladder cancer also experience urine retention because they cannot fully empty their bladder.

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