Research shows that both hypothyroidism and hyperthyroidism can lead to hyperuricemia. The thyroid is a small gland that produces hormones that control many of the body’s metabolic activities. Hyperthyroidism means the body is creating too many of these hormones, while hypothyroidism means it is not creating enough. In hyperthyroidism, hyperuricemia is the result of an increase in urate production. Hypothyroidism causes excess uric acid due to poor blood flow through the kidneys and glomerular dysfunction.

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