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8. Down Syndrome

Many studies show that people with Down syndrome tend to have hyperuricemia. This excessive increase of uric acid appears to begin in early childhood. As the child ages, uric acid levels continue to increase, leading to hyperuricemia. Research reveals the excess uric acid is the result of an overproduction of urate. A 1979 study in the Journal of Rheumatology found that this may be due to glomerular dysfunction. Glomerular refers to the glomerulus, a small ball that helps make up the functional unit of the kidney.

child down syndrome manonallard / Getty Images

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