People with kidney failure may experience persistent itchy skin. For some people, itching is simply a side effect of dry skin. People in the later stages of CKD may develop uremic pruritus or itching caused by an accumulation of toxins. The sensation can happen all over the body or be limited to one spot. It's unpredictable, often appearing and disappearing for varying amounts of time. If the itching is bad enough, it can disrupt sleep and impact the overall quality of life.

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