Pacemakers and implantable cardioverter defibrillators (ICDs) coordinate contractions between the right and left ventricles. Patients with serious arrhythmias may need one of these devices to maintain a normal heartbeat. In advanced cases of cardiomegaly, surgical procedures such as heart valve or coronary bypass surgery can prevent heart failure. When an enlarged heart does not respond to less-invasive treatments, a heart transplant is a final option.

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