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2. Medications

For people with epilepsy, missing a dose of anti-seizure medication is the primary seizure trigger. Individuals without epilepsy can also have seizures because of medications. Some prescription drugs, such as antidepressants, antipsychotics, stimulants, some pain medications, and high doses of insulin, can cause this side effect. Usually, this is because they affect the brain by disturbing the balance between glutamine, which excites seizures, and gamma-aminobutyric acid (GABA), which inhibits them. Drug withdrawal following long-term medication use can also lead to an event.

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