Seizures occur due to disturbances in the brain's neuronal activity. Anyone can have a seizure under certain conditions; not all seizures involve epilepsy, but the condition has many types, each with unique situations that can trigger a seizure. Many triggers vary from person to person, though some are almost universal. It is important to realize that these triggers increase the likelihood of an event but do not immediately result in a seizure.
For people with epilepsy, missing a dose of anti-seizure medication is the primary seizure trigger. Individuals without epilepsy can also have seizures because of medications. Some prescription drugs, such as antidepressants, antipsychotics, stimulants, some pain medications, and high doses of insulin, can cause this side effect. Usually, this is because they affect the brain by disturbing the balance between glutamine, which excites seizures, and gamma-aminobutyric acid (GABA), which inhibits them. Drug withdrawal following long-term medication use can also lead to an event.
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