Dogo Argentinos are generally very healthy. Like other mostly-white colored dogs, they can be afflicted by pigment-related deafness. This affects about 10% of Dogo Argentinos and can cause deafness in one or both ears. As a large dog, they may also suffer from hip dysplasia. Their white fur makes them prone to sunburn, and so owners should make sure they do not spend too much time in direct sunlight.

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