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4. The Creation Of Adam by Michelangelo

Michelangelo painted a total of nine panels of the Sistine Chapel. The most famous of these is the Creation of Adam, a depiction of God creating Adam in the clouds. The outline around God and the other angels depicts a human brain. God is giving Adam life, and researchers believe that Michelangelo meant to say that He gave Adam human intelligence. Michelangelo had extensive knowledge of the human brain thanks to his dissections to study anatomy.

Sistine Chapel Art Lucas Schifres / Getty Images

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