It may surprise you to know that 90% of the body's serotonin is produced in the gut. Serotonin carries messages throughout the body and helps regulate a variety of biological functions, including mood.
An unhealthy gut disrupts mood in the same way that it disrupts sleep, by communication through the vagus nerve and the gut-brain axis. Mood disorders are often treated with SSRIs (serotonin reuptake inhibitors), which frequently have gastrointestinal side effects.

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