Much of the stigma surrounding nightshade vegetables stems from them containing alkaloids. Of these, the most dangerous is solanine, which exists in the leaves, fruits, and tubers of Solanaceae plants.
Ingesting high levels of solanine can cause gastrointestinal issues like diarrhea and vomiting, as well as headaches and hallucinations. Despite this, the vast majority of nightshade vegetables are not capable of delivering enough alkaloids to cause any harm.

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