Vitamin B12 is essential for maintaining healthy red blood cells, brain function, and nerve tissue. Though the body can store B12 for years, people with absorption issues or those following vegetarian or vegan diets are at risk of deficiency. In the U.S., more than 3 million people are affected by a B12 deficiency, also known as cobalamin deficiency.
When doctors cannot trace muscle fatigue to a specific issue such as an over-the-top workout or a recent illness, they may look into a vitamin B12 deficiency. Too little of this vital nutrient can restrict the amount of oxygen reaching the red blood cells, which affects muscle strength to varying degrees.

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