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7. Dopamine Agonists

The hormone prolactin prepares a woman’s body for breastfeeding and is also responsible for PMDD-related mastalgia, uncomfortable swelling and tenderness of the breasts. Dopamine is a chemical that regulates mood, but also inhibits prolactin. Dopamine agonists activate receptors in the brain that release the chemical and alleviate breast-related discomfort for women with PMDD. While these drugs can be effective, side effects such as dizziness and nausea may limit their use.

Dopamine prolactin mastalgia pjjones / Getty Images

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