Avascular necrosis is the death of bone tissue resulting from the decrease or interruption of blood flow to a bone. Injuries, medical treatments, and medications can all cause this symptom. Anyone can be affected by avascular necrosis, but people 30 to 50 years of age are at the greatest risk. Avascular necrosis is irreversible, but treatments can slow the progression and help keep the condition from worsening.
Avascular necrosis can affect the hip, knee, shoulder, hand, or foot. It may occur on one or both sides of the body. Often, people with the early stages of avascular necrosis experience no symptoms. As the disease advances, an individual may feel pain in the affected joint only when he puts weight on it. Eventually, the pain will persist even when laying down. It can range from mild to severe and occurs gradually.
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