De Quervain's tenosynovitis affects the tendons on the thumb side of the wrist, causing intense pain. The condition occurs when the tendons at the base of the thumb become inflamed to the point where they put pressure on the nerves. Swelling and pain can make it difficult to grasp objects. The pain prevents people from using the affected hand. Splinting, ice packs, steroid injections, and pain relievers can help reduce the symptoms; however, some people require surgery.

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