Myasthenia gravis is a rare neuromuscular condition caused by poor communication between nerve endings and muscle fibers, which presents with muscle fatigue and weakness. Unlike some other neuromuscular disorders, myasthenia gravis affects only voluntary muscles or those a person chooses to move, as opposed to those that operate on their own, unconsciously. The symptoms of this disorder can vary dramatically depending on specific muscles or muscle groups it affects.
Every symptom of myasthenia gravis stems from weakened voluntary muscles, which occurs when the immune system attacks the areas where nerve endings connect with muscle fibers. This weakens the signal that tells the muscle to contract. Therefore, people with myasthenia gravis experience weakness. The symptom can be subtle enough that a person may not realize they have a serious disorder. Symptoms usually improve after rest, causing the weakness to come and go throughout the day.
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