Prostate Cancer: Symptoms, Staging, and Treatment
3. T4 and Gleason Score
T4 prostate cancer is the most serious. At this stage, cancer has spread outside of the prostate and seminal vesicles and may be growing in the bladder, rectum, or urethra.
Prostate cancer is also assigned a Gleason score after removal that describes how much the cancer has spread, accounting for the tumor (T), lymph nodes (N), and metastasis (M). For example, N0 means that cancer has not spread to any lymph nodes, while M1 means it has spread to distant parts of the body.
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