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2. Fatigue

Persistent fatigue is one of the most common symptoms reported by people with CLL. This is not the typical tiredness that improves with rest, but a lingering lack of energy that can interfere with daily activities.

Fatigue may be related to anemia, the body’s increased energy demands, or the immune system’s ongoing response to disease. Difficulty concentrating and reduced physical stamina are also common.

young woman staying in bed in her bedroom

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