Around 40 percent of cancer patients experience unexplained weight loss. If they lose up to one-tenth of their total weight over six months or less, this could be the first symptom that something is wrong.
There is no precise cause for this drastic weight loss, but it usually starts with loss of appetite. Other contributing factors include nausea, vomiting, pain, and depression. In advanced cases, the weight loss progresses to cachexia, a combination of weight loss and muscle wasting.

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