Signs and symptoms of Waardenburg syndrome vary according to type. They include changes in eye color such as strikingly blue eyes or two different color irises. Also common to many types are premature greying of the hair or a lock of grey hair -- poliosis. Hearing loss in differing patterns is also common. Type 1 can cause a cleft lip and type 3 may include abnormalities of the arms. Many people with Waardenburg syndrome have wide-spaced eyes, a low hairline, and eyebrows that meet in the middle. Type 4 is associated with intestinal problems.

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