The intensity and severity of fibromyalgia symptoms do not appear to have a relationship with female sex hormones, so scientists are still investigating why fibromyalgia is more common in women and exacerbated by certain stages of the menstrual cycle.
Women with fibromyalgia report higher pain severity and higher fatigue during menstruation. Those with more severe symptoms, such as sleep disturbances, numerous tender points, and psychological distress, typically experience more severe menstrual symptoms.
Other menstrual problems may also be related to the disease. During menopause, when a woman stops having periods, some people with fibromyalgia find their symptoms become more prevalent. According to one study, menopause symptoms nearly double the risk of chronic pain in people with fibromyalgia, back pain, and arthritis.

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