Several medications appear to increase the risk of diverticulitis. Studies note that regular use of acetylsalicylic acid, nonsteroidal anti-inflammatory drugs, steroids, and opiates may lead to diverticular issues. Ibuprofen and naproxen sodium (which are common in non-steroid anti-inflammatory drugs) are associated with higher occurrences of this condition. Gastroenterologists have found that menopausal hormone therapy may contribute to diverticulitis as well.

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