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12. Darkened skin in certain areas

Acanthosis Nigricans is characterized by darkened patches of skin with a velvety texture, commonly found in body folds and creases. Although most people ignore these darkened skin patches, this symptom indicates insulin resistance, a hallmark of Type 2 diabetes. The areas most often affected by this condition include the neck, armpits, elbows, knees, and knuckles. Acanthosis Nigricans serves as a visible warning sign of high insulin levels and should not be overlooked. Early detection and treatment of insulin resistance can help prevent or delay the onset of Type 2 diabetes and its associated complications.

Acanthosis Nigricans Skin. Dark patches on the skin at the elbows known as acanthosis nigricans look like a darkened, velvet-like hyperpigmentation of the skin - scar & Chancriform Skin
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