Nephrogenic diabetes insipidus involves the kidneys simply not responding to vasopressin. Your body can make enough ADH, but the kidneys do not respond correctly. This can be a result of inherited gene changes, chronic kidney disease, low potassium or high calcium levels, a blockage of the urinary tract, or certain medications like lithium. The fourth type of diabetes insipidus is known as disogenic. It deals with the thirst mechanism, which is located in the hypothalamus. If the hypothalamus or pituitary is damaged because of surgery, inflammation, infection, a tumor, or other head injuries than you will experience the symptoms of disogenic diabetes insipidus. Medications and mental health may also be related to the rare disorder.

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