The treatment for May Thurner syndrome is actually focused on treating the DVT associated with vein compression. Blood thinners are recommended to prevent blood clots. Two other treatments are catheter-directed thrombolytic therapy and angioplasty with stenting. In the first, the surgeon guides a catheter into the vein and releases a clot-dissolving medication. If the vein is too narrow after the clot dissolves, the surgeon may perform angioplasty; they use a balloon catheter to open the vein and insert a stent to keep the vein open and avoid future clots.

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