Can Walking Help Prevent Colon Cancer?

Regular brisk walking may reduce the likelihood of colon cancer returning after treatment. In a large randomized clinical trial, participants who followed a structured walking program had a disease-free survival rate of 76% after three years — compared to 69% in the usual-care group.

That 7% improvement is considered clinically meaningful, especially in a cancer population. The trial’s design strengthens the findings: nearly 1,000 people with stage II or III colon cancer were randomly assigned to either walk regularly or continue with standard follow-up care.

Researchers say the results support adding structured exercise to recovery plans. It’s not a replacement for medical treatment, but it’s a low-cost, low-risk strategy with real impact.

The walking program wasn’t intense, but it was consistent. Participants in the exercise group were encouraged to walk briskly for a total of 150 minutes each week — ideally divided into five 30-minute sessions. They wore step counters to track their walking and received regular coaching, either by phone or in person, to help them stay on track.

Participants ranged in age from their 30s to early 80s, and all had completed surgery and chemotherapy for stage II or III colon cancer. The study used a randomized design to compare this group to a standard-care group that received no specific exercise guidance.

While earlier research suggested exercise might help reduce recurrence, this was one of the first large-scale trials to test it directly in a controlled setting.

Participants in the walking group had better outcomes across several key measures. More remained cancer-free, overall survival was higher, and recurrence rates were lower compared to the standard-care group.

The walking program wasn’t a substitute for surgery, chemotherapy, or follow-up care — but it added measurable benefits. Researchers say the results should inform how recovery is supported after treatment ends.

“This is a game changer for cancer care,” said Dr. Kerry Courneya, a lead investigator with the Canadian Cancer Trials Group, in a statement. “We now have high-level evidence that structured exercise can improve outcomes in colon cancer.”

The walking plan wasn’t complicated or extreme. Participants were asked to walk briskly for 150 minutes per week — a level that aligns with public health guidelines. Most split that into five 30-minute sessions.

“Brisk” was defined as a walking pace that raised breathing and heart rate, but still allowed for conversation. Most participants walked outdoors or on treadmills. Many used step counters or pedometers to track their progress.

Importantly, researchers saw benefits even among those who didn’t meet the full weekly target. The results suggest that any increase in physical activity is better than none, especially during recovery.

Colon cancer is one of the leading causes of cancer-related death worldwide. Recurrence is most likely in the first two to three years after treatment — the very window this study addressed. During that time, many patients ask what more they can do beyond attending follow-up appointments.

This research offers a science-backed answer: regular movement may help lower the risk of the cancer returning. Exercise may support immune function, improve insulin regulation, and reduce inflammation — all of which can influence cancer progression.

For people finishing treatment or looking to reduce future risk, walking is a practical option. It doesn’t require a gym, special gear, or prior training. It won’t replace medical care — but it may offer something just as meaningful: a sense of control during an uncertain time.