From persistent fatigue to an enlarged spleen, these are the key signs worth knowing
Because the number of red blood cells decreases, the cells in the brain do not get an adequate amount of oxygen they need for various function. This makes the person affected with Myelofibrosis feel dizzy and lightheaded. Many Patients may find it hard to focus, concentrate or perform challenging mental activities. They may also experience breathing difficulties in the form of shortness of breath. This shortness of breath becomes more obvious when the person tries to do some physical activity. It is also caused by a decreased number of red blood cells.

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