Rectal cancer can cause bleeding, which can lead to a depletion of red blood cells. If a patient complains of fatigue, a physician will likely perform a CBC (complete blood count) blood analysis to measure the white blood cells, red blood cells, and platelets in the body. A diagnosis of anemia means the body is not producing enough healthy red blood cells to carry adequate oxygen to the tissues in the body. This can result in weakness, chest pains or shortness of breath, and lightheadedness or dizziness.

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