Occasionally, the earliest sign that a person has pancreatic cancer is the formation of a blood clot in a large vein, typically within the leg. When a clot develops in the leg in this manner, it is called deep vein thrombosis. Coexisting symptoms include redness, swelling, warmth, and pain in the affected region.
Blood clots can be extremely dangerous, as they may break apart and travel to other organs with potentially life-threatening repercussions. Pulmonary embolisms—blood clots in the lungs—are an example of this.

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