Colon cancer irritates the lining of the intestines as it progresses, resulting in cramping and pain. This sign is not specific to colon cancer. Infections and inflammatory conditions of the bowel, as well as menstruation, can also cause cramping. You can also have colon cancer and experience no pain or cramping at all. However, if you have this symptom for more than a few days, especially if any other signs are present, see a doctor.

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