Around half of the people with PSP immediately present the common symptoms of the condition, which include loss of balance and difficulty walking, impaired speech, and cognitive impairment. The individual may also experience short and long-term memory loss, depression, irritability, personality changes, and apathy. PSP also causes supranuclear ophthalmoplegia, a loss of voluntary eye movement. This eventually results in an inability to look down and a constant wide-eyed expression, with the eyes staring forward.
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