Aplastic anemia requires long term follow up, even after the individual has gone into remission. The disease is somewhat idiopathic, meaning the cause and progression is unclear, and so once a person has it, they may be at risk for getting it again. There's a link between aplastic anemia and paroxysmal nocturnal hemoglobinuria. Research suggests they may overlap, so many medical professionals continue to monitor former patients to ensure that should the latter condition develop, treatment is responsive and timely.

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