Unveiling the Silent Signs of Hemochromatosis

10. Brain Changes and Hemochromatosis

Sometimes iron deposits build in the brain's basal ganglia, structures key to movement, and the cerebellum, which coordinates voluntary motor movement and balance. Researchers disagree over whether systemic iron-loading disorders such as hemochromatosis affect the brain. Some studies indicate that people with multiple sclerosis have higher levels of iron in the basal ganglia. Other studies show that high levels of ferritin, a blood protein that contains iron, may lead to cognitive impairment. People with hemochromatosis often report memory fog, memory loss, depression, lethargy, or a combination of the symptoms. More research is required to thoroughly understand the effects of iron overload in the brain.