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10. Cancer

Rarely, experts make a connection between back pain and cancer. Certain kinds of bone cancer are direct causes, while cancers that have metastasized may cause masses to develop on the vertebrae in the spine or in locations that put pressure on the back. In some cases, chemotherapy drugs cause nerve pain, resulting in a painful condition called peripheral neuropathy.

Decoding Back Pain: Ten Underlying Causes You Should Know gilaxia / Getty Images
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