People with Asperger syndrome enjoy routine, and changes can provoke panic or anxiety. Even something as small as an item moved to a new location can be upsetting. Resistance to change can cause behavioral problems at school or work. When forced to deviate from their routine, children with the disorder may become visibly upset or refuse to accept the change. Often, this resistance lessens as the individual grows up. A dislike of change likely remains, but he or she learns more socially acceptable ways to deal with the issues, as well as coping skills for anxiety.

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