People with Felty syndrome are affected by normochromic normocytic anemia, which means that while they make average-sized red blood cells at a normal rate, the levels are low. Along with that comes, thrombocytopenia, low platelet count, which causes poor blood clotting. These two factors create an environment for an increased risk of ulcers on the lower legs that are hard to heal and could be a source of infection.

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