Causes of Stomach Pain

5. Appendicitis

Appendicitis usually affects children and young adults, though it may occur in people of all ages. The most distinctive symptom is a sharp pain that begins in the middle of the abdomen and travels to the lower right; usually accompanied by fever and fatigue. Infection and inflammation of the appendix causes this condition, and surgery is almost always immediately necessary, as a burst appendix can lead to sepsis and be life-threatening.