Panniculitis is inflammation of the fat layer that lies beneath the skin. It has many causes, one of which is an uncommon type of erythema. When panniculitis also causes red or violet bumps to develop under the skin, physicians classify the condition as erythema nodosum. The bumps grow over the shins in most cases, but may also develop on the arms or other areas. The most common causes of erythema nodosum are streptococcal infection, sarcoidosis, or inflammatory bowel disease. Treatment involves elevation of the affected limb and application of cold compresses. Nonsteroidal anti-inflammatory drugs may assist with pain and swelling.

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